Son of Frank Zappa and a heavy metal disciple of Eddie Van Halen and Steve Vai, Dweezil released his first album, Haviní a Bad Day, in 1986. He worked a stint as a VJ on MTV, appeared in the films Pretty in Pink and The Running Man, and had a brief sojourn in TV situation comedy with his sister Moon Unit, on 1988-1989ís Normal Life. Dweezil also issued his second album, My Guitar Wants to Kill Your Mama, in 1988, following it in 1991 with Confessions, and subsequently took a break from solo recording.
He worked in television for a time, composing the theme song to the sadly short-lived Ben Stiller Show and voicing the character of Ajax on the brilliant USA Network animated series Duckman. He next formed the band Z with brother Ahmet on vocals; the group released two albums together: 1994ís Shampoohorn and 1996ís Music for Pets.
In addition to his work as a session guitarist, Zappa busied himself with Happy Hour ( a TV show for the USA Network which debuted in 1999 and was co-hosted with Ahmet ), and his first solo album in nine years, 2000ís mostly instrumental Automatic. Following this, Dweezil fell back out of the public eye and re-dedicated himself to learning guitar, changing his style a bit and adopting many of his fatherís picking techniques.
In 2005, he assembled a crack band of younger players and recruited FZ alumni Steve Vai, Terry Bozzio, and Napoleon Murphy Brock for the critically acclaimed Zappa Plays Zappa tour which hit the road in the summer of 2006. The band (with Brock ostensibly as the frontman) performed an entire program of Frank Zappa compositions with Vai and Bozzio appearing as guests and Dweezil as lead guitarist/bandleader. Between legs of that tour, he released Go with What You Know (2006), easily his most ambitious album to date. A studio version and DVD of Zappa Plays Zappa appeared in 2008.